Advances in Medicinal Chemistry

Description

The medicinal chemistry field focuses on the creation, development, and synthesis of pharmaceuticals. To identify, develop, and synthesize chemical agents with therapeutic uses as well as to assess the qualities of already existing medications, this subject combines knowledge from the fields of chemistry and pharmacology. The main topics of pharmaceutical drug research are presented in a thorough and well-illustrated manner in the book "Medicinal Chemistry." It will be beneficial as a textbook for pharmacy students and an overview for research scientists considering careers in the pharmaceutical sector. In order to provide readers with a comprehensive grasp of contemporary medicinal medications, the book unifies the chemical and pharmacological aspects of drugs and links the fields of organic chemistry, biochemistry, and biology with the clinical areas. One of humanity's most significant aspirations is treating illness and pain. People have used potions, natural ingredients, and even the dust from mummies to treat illnesses since the dawn of time. Some herbal concoctions did have medicinal properties, but the healing powers of remedies were frequently attributed to ghosts and other supernatural beings. Scientists started looking into possibilities in the 1800s to identify any substances that might be present and be responsible for the observed healing. Therefore, the study of naturally occurring substances that successfully treated human illnesses was the starting point for medicinal chemistry in its early stages. At a time when instrumental methods of analysis were not accessible, the research was time-consuming and required extensive sample purification and structure determination. In order to avoid using humans in trials, screening techniques for chemical efficacy against disease have to be devised. The history of drug creation is a foundation for the book, but little prior knowledge is assumed. The emphasis is on expanding our understanding of how medications work at the molecular level before providing a general summary of current concerns and the most frequently employed methods.