Essentials of Structure and Mechanism of Enzymes

Description

Enzymes have long been researched by measuring their activity, which has advanced the field of "enzyme kinetics." The majority of chemical catalysts can catalyse a variety of processes. They frequently lack much discrimination. In contrast, enzymes typically catalyse only specific reactions and are quite selective. The shapes of the enzyme molecules are what give them their selectivity. An enzyme is a protein that lowers activation energy (Ea) levels to catalyse the chemical reactions between biomolecules, hence facilitating a cellular metabolic process. Some enzymes reverse biological reactions by drastically lowering the activation energy. Amino acids, which make up enzymes, are joined in a linear chain by amide (peptide) bonds. Polypeptides or proteins are the names given to the resulting amino acid chain. The relevant gene's DNA sequence encodes the protein's precise amino acid sequence. The chemical transformations and subsequent steps produced by an enzyme's action on a substrate are known as enzyme mechanisms. In theory, the mechanism of enzyme catalysis is comparable to other types of chemical catalysis, such as combining various types of catalysis. The kinetic and thermodynamic characteristics of enzymes are determined while determining their processes. The book provides an overview of the present knowledge of enzymology by discussing the structure and mechanism of enzymes.