Pharmacogenomics: An Introduction and Clinical Perspective

Description

By covering topics from individual molecules to systemic diseases, from fundamental concepts to advanced technologies, this book intends to provide a practical, state-of-the-art, and integrative view of the application of pharmacogenomics in drug discovery and development. The second aspect composes a large part of this book: a focus on how pharmacogenomics can be used in therapeutics of diseases. These diseases include cardiovascular diseases, cancer, neurological diseases, gastrointestinal disorders, autoimmune diseases, and infectious diseases. Comprehensive information for each disease system is discussed, including biomarkers involved in the disease and the associations among genes, drugs, diseases, drug response phenotypes, and the environment.